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CS-W001157 4
Total: USD 88.00

3,4-Dihydronaphthalen-1-one

  • CAS No. 529-34-0

  • Cat. No. CS-0226151
  • Purity≥96%
  • MDL No.MFCD00001688

*For research and further manufacturing use only, not for direct human use.

3,4-Dihydronaphthalen-1-one|CS-0226151

Structure of 529-34-0

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General Information

  • CAS No. 529-34-0
  • Cat. No. CS-0226151
  • Purity ≥96%
  • MDL No. MFCD00001688
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₀O
  • Molecular Weight 146.19
  • Synonym(s) 3,4-Dihydro-1(2H)-naphthalenone
  • SMILES O=C1CCCC2=C1C=CC=C2

Application

3,4-Dihydronaphthalen-1-one serves as a versatile scaffold for the synthesis of biologically relevant heterocycles and natural product analogs. Its conjugated enone system enables reliable Michael additions, Diels–Alder cycloadditions, and selective reductions, facilitating access to complex polycyclic frameworks. The compound exhibits good bench stability and is readily purified by flash chromatography, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development workflows.

Synthesis

  • Route1

    References

    • Journal of the American Chemical Society, , vol. 123, # 31 p. 7725 - 7726
  • Route2
    • null|null
      56685-73-5
    • ~99%
    • In-stock
      3,4-Dihydronaphthalen-1-one|CS-0226151
      529-34-0

    References

    • Kirihara, Masayuki; Noguchi, Takuya; Okajima, Nobuhiro; Naito, Sayuri; Ishizuka, Yuki; Harano, Aiko; Tsukiji, Hiroyuki; Takizawa, Ryu Tetrahedron, 2012 , vol. 68, # 5 p. 1515 - 1520
  • Route3

    References

    • Tsunoyama, Hironori; Tsukuda, Tatsuya; Sakurai, Hidehiro Chemistry Letters, 2007 , vol. 36, # 2 p. 212 - 213

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.2056
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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