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Structure of 53234-56-3
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6-Chloro-5-cyanopicolinic acid features a pyridine core functionalized with chlorine and cyano groups at adjacent positions, enabling high reactivity in coupling processes. This electron-deficient heterocycle integrates readily into pharmaceutical scaffolds and advanced materials, offering enhanced solubility and stability under standard conditions.
6-Chloro-5-cyanopicolinic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into heterocyclic scaffolds via standard coupling and cyclization protocols. Its ortho-functionalized pyridine core offers enhanced reactivity for palladium-catalyzed cross-couplings and facilitates downstream derivatization under mild conditions. Bench-stable and readily purified by recrystallization, it functions as a key intermediate in the synthesis of bioactive molecules, particularly those requiring halogenated nitrile motifs for targeted functionalization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: