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CS-W001157 4
Total: USD 88.00

2H-Benzo[b][1,4]thiazin-3(4H)-one

  • CAS No. 5325-20-2

  • Cat. No. CS-0085251
  • Purity≥98%
  • MDL No.MFCD00006698

*For research and further manufacturing use only, not for direct human use.

2H-Benzo[b][1,4]thiazin-3(4H)-one|CS-0085251

Structure of 5325-20-2

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General Information

  • CAS No. 5325-20-2
  • Cat. No. CS-0085251
  • Purity ≥98%
  • MDL No. MFCD00006698
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇NOS
  • Molecular Weight 165.21
  • Synonym(s) diethyl (acetylamino)(2-chlorobenzyl)propanedioate
  • SMILES O=C1CSC2=CC=CC=C2N1

Description

2H-1,4-Benzothiazin-3(4H)-one derivatives were synthesized and tested for calcium antagonistic and calmodulin antagonistic activities.

Synthesis

  • Route1
    • null|null
      79-11-8
    • null|null
      137-07-5
    • ~83%
    • In-stock
      2H-Benzo[b][1,4]thiazin-3(4H)-one|CS-0085251
      5325-20-2

    References

    • Gowda; Khader; Kalluraya; Shree, Padma; Shabaraya European Journal of Medicinal Chemistry, 2011 , vol. 46, # 9 p. 4100 - 4106
  • Route2
    • In-stock
      2-Iodoaniline|CS-W007318
      615-43-0
    • null|null
      2365-48-2
    • ~63%
    • In-stock
      2H-Benzo[b][1,4]thiazin-3(4H)-one|CS-0085251
      5325-20-2

    References

    • Huang, Wei-Sheng; Xu, Rongsong; Dodd, Rory; Shakespeare, William C. Tetrahedron Letters, 2013 , vol. 54, # 38 p. 5214 - 5216
  • Route3
    • 2-((2-Nitrophenyl)thio)acetic acid|CS-0157963
      6375-65-1
    • ~44%
    • In-stock
      2H-Benzo[b][1,4]thiazin-3(4H)-one|CS-0085251
      5325-20-2

    References

    • El-Subbagh; Abadi; Al-Khawad; Al-Rashood Archiv der Pharmazie, 1999 , vol. 332, # 1 p. 19 - 24

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   1.7308
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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