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Structure of 53277-47-7
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Methyl 2-chloro-6-methylnicotinate features a chlorinated pyridine core with strategic methylation at the 6-position, enhancing electronic and steric control. This electron-deficient heterocycle integrates readily into synthetic sequences requiring regioselective functionalization. The ester group enables direct derivatization or transformation under standard conditions.
Methyl 2-chloro-6-methylnicotinate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted nicotinates and pyridine derivatives. Its chlorine at C2 facilitates nucleophilic substitution, while the methyl group at C6 offers a handle for further functionalization. The ester functionality supports transformations such as reduction or hydrolysis, and the molecule exhibits good bench stability and ease of purification—ideal for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: