Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-Bromo-5-nitronaphthalene

  • CAS No. 5328-76-7

  • Cat. No. CS-0041432
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-Bromo-5-nitronaphthalene|CS-0041432

Structure of 5328-76-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 5328-76-7
  • Cat. No. CS-0041432
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₆BrNO₂
  • Molecular Weight 252.06
  • Synonym(s) 5-bromo-1-nitro-naphthalene
  • SMILES O=[N+](C1=CC=CC2=C(Br)C=CC=C12)[O-]

Description

1-Bromo-5-nitronaphthalene features a nitro group positioned para to the bromine on a naphthalene core, creating a highly electron-deficient aromatic system. This configuration enables efficient cross-coupling reactions under palladium catalysis, delivering functionalized naphthalenes with high regioselectivity. The molecule exhibits excellent stability under standard bench conditions and facilitates direct incorporation into complex molecular architectures.

Application

1-Bromo-5-nitronaphthalene serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions to construct biaryl scaffolds. The bromo group exhibits high reactivity in Suzuki, Stille, and Negishi couplings, while the nitro group provides orthogonal functionality for subsequent reduction or electrophilic substitution. Its bench-stable nature and compatibility with diverse reaction conditions make it well-suited for medicinal chemistry and materials synthesis workflows.

Synthesis

  • Route1
    • null|null
      86-57-7
    • ~50%
    • In-stock
      1-Bromo-5-nitronaphthalene|CS-0041432
      5328-76-7

    References

    • Gao, Xingming; Zhang, Yanling; Wang, Binghe New Journal of Chemistry, 2005 , vol. 29, # 4 p. 579 - 586
  • Route2
    • 5-Nitronaphthalen-1-amine|CS-0159295
      3272-91-1
    • ~%
    • In-stock
      1-Bromo-5-nitronaphthalene|CS-0041432
      5328-76-7

    References

    • Hodgson; Walker Journal of the Chemical Society, 1933 , p. 1620
  • Route3
    • null|null
      86-57-7
    • null|null
      7726-95-6
    • ~%
    • In-stock
      1-Bromo-5-nitronaphthalene|CS-0041432
      5328-76-7

    References

    • Guareschi Justus Liebigs Annalen der Chemie, 1884 , vol. 222, p. 283 Gazzetta Chimica Italiana, 1886 , vol. 16, p. 151

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H303-H318
Precautionary Statements : P280-P305+P351+P338-P310-P312

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   43.14
  • LogP   3.5105
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1-Bromo-5-nitronaphthalene sigma1-Bromo-5-nitronaphthalene manufacturer1-Bromo-5-nitronaphthalene price1-Bromo-5-nitronaphthalene structure1-Bromo-5-nitronaphthalene SDSbuy 1-Bromo-5-nitronaphthalene1-Bromo-5-nitronaphthalene supplier1-Bromo-5-nitronaphthalene uses1-Bromo-5-nitronaphthalene molecular weightprice of 1-Bromo-5-nitronaphthalene1-Bromo-5-nitronaphthalene chemical name formula of 1-Bromo-5-nitronaphthalene
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label