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CS-W001157 4
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Ethyl 2-bromobutanoate

  • CAS No. 533-68-6

  • Cat. No. CS-W010634
  • Purity≥98%
  • MDL No.MFCD00000155

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-bromobutanoate|CS-W010634

Structure of 533-68-6

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General Information

  • CAS No. 533-68-6
  • Cat. No. CS-W010634
  • Purity ≥98%
  • MDL No. MFCD00000155
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁BrO₂
  • Molecular Weight 195.06
  • Synonym(s) Ethyl-α-bromobutyrate
  • SMILES CCC(Br)C(OCC)=O

Description

Ethyl 2-bromobutanoate serves as a key alkylating agent in synthetic organic chemistry, featuring a reactive bromine atom at the α-position to the ester group. This configuration enables efficient carbon–carbon bond formation under mild conditions, facilitating the construction of complex molecular architectures. The compound exhibits excellent stability under standard bench protocols and integrates seamlessly into multi-step synthesis workflows.

Application

Ethyl 2-bromobutanoate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to β-branched alkylated scaffolds. The α-bromo ester functionality facilitates SN₂ reactions with nucleophiles, including amines and thiols, while maintaining compatibility with common protecting groups. Its bench-stable nature and straightforward purification support reliable use in multi-step syntheses, particularly for constructing substituted heterocycles and functionalized carboxylic acid derivatives.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS05,GHS07
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H302-H315-H318-H335-H412
Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P273-P280-P304+P340-P330-P362-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   1.723
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

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