Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Chloro-2-(hydroxymethyl)phenol

  • CAS No. 5330-38-1

  • Cat. No. CS-0179475
  • Purity≥95%
  • MDL No.MFCD00021967

*For research and further manufacturing use only, not for direct human use.

4-Chloro-2-(hydroxymethyl)phenol|CS-0179475

Structure of 5330-38-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 5330-38-1
  • Cat. No. CS-0179475
  • Purity ≥95%
  • MDL No. MFCD00021967
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇ClO₂
  • Molecular Weight 158.58
  • Synonym(s) 5-Chlorosalicyl alcohol
  • SMILES OCC1=CC(Cl)=CC=C1O

Description

4-Chloro-2-(hydroxymethyl)phenol offers a reactive hydroxymethyl group flanked by a chlorine substituent, enabling selective functionalization in synthetic pathways. This ortho-chlorinated phenolic scaffold provides enhanced stability and targeted reactivity for applications in medicinal chemistry and materials synthesis.

Application

4-Chloro-2-(hydroxymethyl)phenol serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to functionalized aromatic scaffolds. The ortho-hydroxymethyl group facilitates direct derivatization via oxidation, etherification, or coupling reactions, while the chloro substituent supports palladium-catalyzed cross-couplings. Its bench-stable nature and compatibility with diverse reaction conditions make it a practical choice for multi-step syntheses requiring selective functionalization.

Synthesis

  • Route1

    References

    • Choi, Young Lok; Lim, Hye Sun; Lim, Hwan Jung; Heo, Jung-Nyoung Organic Letters, 2012 , vol. 14, # 19 p. 5102 - 5105,4
  • Route2

    References

    • Kemp, D. S.; Carey, Robert I.; Dewan, John C.; Galakatos, Nicholas G.; Kerkman, Daniel; Leung, See-Lap Journal of Organic Chemistry, 1989 , vol. 54, # 7 p. 1589 - 1603
  • Route3
    • null|null
      50-00-0
    • null|null
      106-48-9
    • ~80%
    • In-stock
      4-Chloro-2-(hydroxymethyl)phenol|CS-0179475
      5330-38-1

    References

    • Li, Hui-Jing; Wu, Ying-Ying; Wu, Qin-Xi; Wang, Rui; Dai, Chun-Yang; Shen, Zhi-Lun; Xie, Cheng-Long; Wu, Yan-Chao Organic and Biomolecular Chemistry, 2014 , vol. 12, # 19 p. 3100 - 3107

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   40.46
  • LogP   1.5379
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Chloro-2-(hydroxymethyl)phenol sigma4-Chloro-2-(hydroxymethyl)phenol manufacturer4-Chloro-2-(hydroxymethyl)phenol price4-Chloro-2-(hydroxymethyl)phenol structure4-Chloro-2-(hydroxymethyl)phenol SDSbuy 4-Chloro-2-(hydroxymethyl)phenol4-Chloro-2-(hydroxymethyl)phenol supplier4-Chloro-2-(hydroxymethyl)phenol uses4-Chloro-2-(hydroxymethyl)phenol molecular weightprice of 4-Chloro-2-(hydroxymethyl)phenol4-Chloro-2-(hydroxymethyl)phenol chemical name formula of 4-Chloro-2-(hydroxymethyl)phenol
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label