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Structure of 53316-51-1
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4,5-Dimethyl-1H-imidazole hydrochloride is a bench-stable, moisture-tolerant heterocyclic salt featuring two methyl groups at the 4 and 5 positions of the imidazole ring. This substitution pattern enhances electron density at the nitrogen atoms, promoting strong coordination in metal-ligand systems. The hydrochloride counterion improves solubility in polar solvents, facilitating use in catalytic reactions, synthetic intermediates, and ligand design.
4,5-Dimethyl-1H-imidazole hydrochloride serves as a robust building block for imidazole-based scaffolds in medicinal chemistry and catalysis. Its stable, crystalline form facilitates handling and purification, while the protonated nitrogen enhances solubility in polar solvents. The methyl groups provide steric protection and tune electronic properties, enabling reliable coupling reactions and serving as a platform for further functionalization in drug discovery and ligand design workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: