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CS-W001157 4
Total: USD 88.00

4,5-Dimethyl-1H-imidazole hydrochloride

  • CAS No. 53316-51-1

  • Cat. No. CS-0153598
  • Purity≥95%
  • MDL No.MFCD09743540
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4,5-Dimethyl-1H-imidazole hydrochloride|CS-0153598

Structure of 53316-51-1

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Description

4,5-Dimethyl-1H-imidazole hydrochloride is a bench-stable, moisture-tolerant heterocyclic salt featuring two methyl groups at the 4 and 5 positions of the imidazole ring. This substitution pattern enhances electron density at the nitrogen atoms, promoting strong coordination in metal-ligand systems. The hydrochloride counterion improves solubility in polar solvents, facilitating use in catalytic reactions, synthetic intermediates, and ligand design.

Application

4,5-Dimethyl-1H-imidazole hydrochloride serves as a robust building block for imidazole-based scaffolds in medicinal chemistry and catalysis. Its stable, crystalline form facilitates handling and purification, while the protonated nitrogen enhances solubility in polar solvents. The methyl groups provide steric protection and tune electronic properties, enabling reliable coupling reactions and serving as a platform for further functionalization in drug discovery and ligand design workflows.

General Information

  • CAS No. 53316-51-1
  • Cat. No. CS-0153598
  • Purity ≥95%
  • MDL No. MFCD09743540
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉ClN₂
  • Molecular Weight 132.59
  • Synonym(s) 4,5-Dimethylimidazole hydrochloride
  • SMILES CC1=C(C)N=CN1.Cl

Computational Chemistry Data

  • TPSA   28.68
  • LogP   1.44834
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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