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Structure of 5332-25-2
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6-Bromoquinoline is a halogenated heterocycle featuring a bromine atom at the 6-position of the quinoline core. This electron-deficient scaffold integrates readily into cross-coupling reactions, serving as a key building block in pharmaceutical synthesis and materials science. The para-brominated configuration enhances reactivity in palladium-catalyzed transformations while maintaining stability under standard handling conditions.
6-Bromoquinoline serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions such as Suzuki, Stille, and Negishi couplings. Its bromine substituent offers high reactivity under standard conditions while maintaining bench stability, facilitating efficient construction of biaryl and heteroaryl architectures. The quinoline core provides inherent π-conjugation and metal-chelating properties, making it valuable for synthesizing fluorescent probes, kinase inhibitors, and organic semiconductors.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: