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Structure of 5345-42-6
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1-Methoxy-3-methyl-2-nitrobenzene features a nitro group flanked by electron-donating methoxy and methyl substituents, creating a unique electronic profile ideal for directed ortho-metalation. This arrangement enables selective functionalization in complex synthesis pathways, particularly in pharmaceutical intermediates and advanced materials. The compound exhibits excellent stability under standard bench conditions and demonstrates favorable solubility in common organic solvents.
1-Methoxy-3-methyl-2-nitrobenzene serves as a versatile ortho-substituted aromatic building block in synthetic organic chemistry. Its nitro group enables subsequent reduction to an amino function, while the methoxy and methyl groups provide steric and electronic modulation for directed metallation or electrophilic substitution. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for use in pharmaceutical intermediate synthesis and heterocyclic scaffold construction.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H319
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Precautionary Statements : P264-P270-P280-P301+P310-P305+P351+P338-P330-P337+P313-P501
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Lot numbers can be found on the outside label of a product: