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Structure of 53484-18-7
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1-Methyl-1H-benzo[d]imidazole-6-carboxylic acid features a fused heterocyclic core with a methylated imidazole ring and a carboxylic acid group at the 6-position, enabling direct conjugation or salt formation. This scaffold exhibits enhanced solubility and metabolic stability compared to unsubstituted analogs, making it valuable for medicinal chemistry applications. The electron-deficient aromatic system supports efficient coupling reactions in peptide and macrocycle synthesis.
1-Methyl-1H-benzo[d]imidazole-6-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its carboxylic acid functionality enables direct amidation, esterification, or coupling reactions, while the methylated benzoimidazole core offers enhanced metabolic stability and favorable solubility. The compound exhibits good bench stability and facilitates efficient purification via standard chromatographic methods, supporting its use in multi-step syntheses of bioactive molecules and functionalized scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: