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Structure of 5370-25-2
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2-Acetyl-5-bromothiophene features a bromine substituent at the 5-position and an acetyl group at the 2-position, creating a bifunctional thiophene scaffold with enhanced reactivity. This electron-deficient heterocycle integrates readily into cross-coupling reactions and serves as a key intermediate in synthesizing functionalized thienyl compounds for materials science and medicinal chemistry applications.
2-Acetyl-5-bromothiophene serves as a versatile building block in synthetic organic chemistry, enabling direct functionalization at the 5-position via palladium-catalyzed cross-coupling reactions. The bromine atom facilitates efficient C–C bond formation, while the acetyl group provides a handle for further transformations such as reduction or condensation. Its stability under standard reaction conditions and compatibility with diverse coupling partners make it well-suited for constructing complex heterocyclic scaffolds and advanced intermediates in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: