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CS-W001157 4
Total: USD 88.00

Benzylmethyl ether

  • CAS No. 538-86-3

  • Cat. No. CS-W013553
  • Purity≥97%
  • MDL No.MFCD00025901
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Benzylmethyl ether|CS-W013553

Structure of 538-86-3

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Description

(Methoxymethyl)benzene serves as a robust, bench-stable aryl protecting group for alcohols and amines. This aromatic ether features a methoxymethyl moiety tethered to a benzene ring, offering enhanced stability under acidic conditions while enabling selective deprotection via mild acidolysis. The electron-donating methoxy group modulates reactivity, facilitating its integration into complex synthetic sequences without interference from competing functional groups.

Application

(Methoxymethyl)benzene serves as a stable, bench-ready benzyl-type protecting group for alcohols and amines, enabling selective deprotection under mild acidic conditions. Its orthogonal stability to many reaction conditions facilitates its use in complex synthesis workflows. The methoxymethyl moiety functions as a versatile building block in the construction of heterocyclic scaffolds and medicinal chemistry libraries.

General Information

  • CAS No. 538-86-3
  • Cat. No. CS-W013553
  • Purity ≥97%
  • MDL No. MFCD00025901
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀O
  • Molecular Weight 122.16
  • Synonym(s) None
  • SMILES COCC1=CC=CC=C1

Computational Chemistry Data

  • TPSA   9.23
  • LogP   1.833
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02
Signal Word : Danger
UN#: 3271
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226
Precautionary Statements : P210-P240-P241-P280-P370+P378

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