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Structure of 5396-89-4
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Benzyl acetoacetate serves as a key synthetic intermediate featuring a reactive β-keto ester moiety flanked by a benzyl group. This combination enables efficient Michael additions, Claisen condensations, and heterocycle formations under mild conditions. The benzyl protection enhances stability during storage and reaction handling, while the enolizable carbonyl system supports diverse transformations in medicinal chemistry and natural product synthesis.
Benzyl acetoacetate serves as a versatile synthon in organic synthesis, enabling efficient construction of substituted pyranones and heterocyclic scaffolds via Claisen condensation and Michael addition protocols. Its benzyl ester functionality provides enhanced bench stability and facilitates straightforward purification, while the β-ketoester motif exhibits predictable reactivity in standard coupling and cyclization reactions. Widely employed in medicinal chemistry and natural product synthesis, it functions as a key building block for bioactive molecule assembly.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: