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CS-W001157 4
Total: USD 88.00

4-Hydroxyfuran-2(5H)-one

  • CAS No. 541-57-1

  • Cat. No. CS-W013716
  • Purity≥95%
  • MDL No.MFCD00052187

*For research and further manufacturing use only, not for direct human use.

4-Hydroxyfuran-2(5H)-one|CS-W013716

Structure of 541-57-1

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General Information

  • CAS No. 541-57-1
  • Cat. No. CS-W013716
  • Purity ≥95%
  • MDL No. MFCD00052187
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₄O₃
  • Molecular Weight 100.07
  • Synonym(s) 5-hydroxyfuran-3(2H)-one
  • SMILES O=C1OCC(O)=C1

Description

Sodium pyrophosphate dibasic has been used:as a setting retardantas a component of STOP-washing buffer for in gel kinase assayas protease and phosphatase inhibitor in the preparation of western blot lysis buffer

Application

4-Hydroxyfuran-2(5H)-one serves as a versatile scaffold for the synthesis of bioactive heterocycles and natural product analogs. Its enolizable carbonyl and electron-rich dienone system facilitates electrophilic substitution, Michael additions, and cycloaddition reactions. The compound exhibits bench stability and enables straightforward functionalization under mild conditions, making it a practical building block in medicinal chemistry and synthetic methodology development.

Synthesis

  • Route1

    References

    • Schmidt, Diane Grob; Zimmer, Hans Synthetic Communications, 1981 , vol. 11, # 5 p. 385 - 390
  • Route2
    • null|null
      128766-63-2
    • ~78%
    • In-stock
      4-Hydroxyfuran-2(5H)-one|CS-W013716
      541-57-1

    References

    • Sato; Sakaki; Takayama; Kobayashi; Suzuki; Kaneko Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 1 p. 94 - 98
  • Route3
    • null|null
      35594-15-1
    • ~%
    • In-stock
      4-Hydroxyfuran-2(5H)-one|CS-W013716
      541-57-1

    References

    • Heterocycles, , vol. 24, # 5 p. 1429 - 1431

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   -0.0149
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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