2-Chloro-4H-pyrido[1,2-a]pyrimidin-4-one

Name: 2-Chloro-4H-pyrido[1,2-a]pyrimidin-4-one
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 5418-94-0
Cat. No. CS-0071942
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Chloro-4H-pyrido[1,2-a]pyrimidin-4-one|CS-0071942

Structure of 5418-94-0

Size

Price

Quantity

* Please select Quantity before adding items.

Description

2-Chloro-4H-pyrido[1,2-a]pyrimidin-4-one is a heterocyclic scaffold featuring a chlorine atom at the 2-position and a carbonyl group at the 4-position, enabling direct incorporation into kinase inhibitors and antiviral agents. The electron-deficient pyrimidine core supports efficient coupling reactions under standard conditions. This bench-stable compound serves as a key intermediate in medicinal chemistry campaigns targeting purine analogs.

Application

2-Chloro-4H-pyrido[1,2-a]pyrimidin-4-one serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its chloro-substituted pyridopyrimidinone core enables efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. The scaffold exhibits excellent bench stability, facilitates straightforward purification, and demonstrates broad compatibility with diverse functional groups, making it well-suited for the synthesis of kinase inhibitors and other bioactive compounds.

General Information

CAS No. 5418-94-0
Cat. No. CS-0071942
Purity ≥98%
MDL No. None
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₅ClN₂O
Molecular Weight 180.59
Synonym(s) 2-cloro-4H-pirido
SMILES O=C1N(C=CC=C2)C2=NC(Cl)=C1

Computational Chemistry Data

TPSA 34.37
LogP 1.3479
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

2-Chloro-4H-pyrido[1,2-a]pyrimidin-4-one sigma2-Chloro-4H-pyrido[1,2-a]pyrimidin-4-one manufacturer2-Chloro-4H-pyrido[1,2-a]pyrimidin-4-one price2-Chloro-4H-pyrido[1,2-a]pyrimidin-4-one structure2-Chloro-4H-pyrido[1,2-a]pyrimidin-4-one SDSbuy 2-Chloro-4H-pyrido[1,2-a]pyrimidin-4-one2-Chloro-4H-pyrido[1,2-a]pyrimidin-4-one supplier2-Chloro-4H-pyrido[1,2-a]pyrimidin-4-one uses2-Chloro-4H-pyrido[1,2-a]pyrimidin-4-one molecular weightprice of 2-Chloro-4H-pyrido[1,2-a]pyrimidin-4-one2-Chloro-4H-pyrido[1,2-a]pyrimidin-4-one chemical name formula of 2-Chloro-4H-pyrido[1,2-a]pyrimidin-4-one

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Chloro-4H-pyrido[1,2-a]pyrimidin-4-one

CAS No. 5418-94-0

Recommended Products