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CS-W001157 4
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6-Methoxy-3,4-dihydroquinolin-2(1H)-one Cilostazol Impurity

  • CAS No. 54197-64-7

  • Cat. No. CS-0229376
  • Purity≥98%
  • MDL No.MFCD02179395

*For research and further manufacturing use only, not for direct human use.

6-Methoxy-3,4-dihydroquinolin-2(1H)-one Cilostazol  Impurity|CS-0229376

Structure of 54197-64-7

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General Information

  • CAS No. 54197-64-7
  • Cat. No. CS-0229376
  • Purity ≥98%
  • MDL No. MFCD02179395
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₁NO₂
  • Molecular Weight 177.20
  • Synonym(s) 6-methoxy-3,4-dihydro-1H-quinolin-2-one
  • SMILES O=C1NC2=C(C=C(OC)C=C2)CC1

Synthesis

  • Route1
    • 6-Hydroxy-3,4-dihydroquinolin-2(1H)-one Cilostazol  Impurity|CS-0229375
      54197-66-9
    • null|null
      77-78-1
    • ~82%
    • 6-Methoxy-3,4-dihydroquinolin-2(1H)-one Cilostazol  Impurity|CS-0229376
      54197-64-7

    References

    • Pfizer Products Inc. Patent: EP1175417 B1, 2004 ; Location in patent: Page 27 ;
  • Route2
    • null|null
      457622-19-4
    • ~62%
    • 6-Methoxy-3,4-dihydroquinolin-2(1H)-one Cilostazol  Impurity|CS-0229376
      54197-64-7

    References

    • Fujita, Ken-Ichi; Takahashi, Yoshinori; Owaki, Maki; Yamamoto, Kazunari; Yamaguchi, Ryohei Organic Letters, 2004 , vol. 6, # 16 p. 2785 - 2788
  • Route3
    • null|null
      1493774-34-7
    • ~55%
    • 6-Methoxy-3,4-dihydroquinolin-2(1H)-one Cilostazol  Impurity|CS-0229376
      54197-64-7

    References

    • Cismesia, Megan A.; Ischay, Michael A.; Yoon, Tehshik P. Synthesis (Germany), 2013 , vol. 45, # 19 art. no. 3889, p. 2699 - 2705

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   1.5799
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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