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CS-W001157 4
Total: USD 88.00

3-Iodo-2-nitropyridine

  • CAS No. 54231-34-4

  • Cat. No. CS-0041449
  • Purity≥98%
  • MDL No.MFCD08061318
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Iodo-2-nitropyridine|CS-0041449

Structure of 54231-34-4

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Description

3-Iodo-2-nitropyridine features a nitro group at the 2-position and an iodine atom at the 3-position, creating a highly reactive site for cross-coupling transformations. This electron-deficient pyridine scaffold enables efficient palladium-catalyzed reactions, delivering functionalized heterocycles with high regiocontrol. The compound exhibits stability under standard bench conditions and serves as a key building block in medicinal chemistry and materials science.

Application

3-Iodo-2-nitropyridine serves as a versatile building block in cross-coupling chemistry, enabling efficient access to substituted pyridines via palladium-catalyzed reactions. The iodide group facilitates reliable C–C and C–heteroatom bond formation, while the ortho-nitro group provides a handle for selective reduction and subsequent heterocycle elaboration. Its bench-stable nature and compatibility with diverse functional groups make it a practical choice for medicinal chemistry and process development workflows.

General Information

  • CAS No. 54231-34-4
  • Cat. No. CS-0041449
  • Purity ≥98%
  • MDL No. MFCD08061318
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃IN₂O₂
  • Molecular Weight 249.99
  • Synonym(s) 2-Nitro-3-jodpyridin
  • SMILES O=[N+](C1=NC=CC=C1I)[O-]

Computational Chemistry Data

  • TPSA   56.03
  • LogP   1.5944
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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