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*For research and further manufacturing use only, not for direct human use.
Structure of 5435-36-9
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2-(7-Methyl-1H-indol-3-yl)acetic acid features a benzene-fused indole core with a methyl group at the 7-position, enhancing electron density and metabolic stability. The pendant acetic acid moiety enables direct conjugation or derivatization under standard coupling conditions. This structure integrates seamlessly into bioactive molecule scaffolds, particularly in CNS-targeted pharmaceuticals and synthetic intermediates requiring lipophilic, aromatic character.
2-(7-Methyl-1H-indol-3-yl)acetic acid serves as a versatile building block for indole-based bioactive molecules, enabling efficient access to pharmaceutically relevant scaffolds. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions under standard conditions. The 7-methyl substitution enhances metabolic stability and modulates electronic properties, while the indole core provides inherent π-stacking and hydrogen-bonding capacity. Bench-stable and readily purified by recrystallization, it functions reliably in medicinal chemistry campaigns targeting CNS agents and kinase inhibitors.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P501
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Lot numbers can be found on the outside label of a product: