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Structure of 5453-88-3
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Ethyl 1-methyl-2-oxocyclopentanecarboxylate features a strained cyclopentanone core with an α,β-unsaturated ester moiety, enabling direct functionalization at the enolizable α-position. This bench-stable reagent integrates readily into asymmetric synthesis workflows, offering high regiocontrol in aldol and Michael additions.
Ethyl 1-methyl-2-oxocyclopentanecarboxylate serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of cyclopentane-containing scaffolds. Its enolizable α-keto ester functionality facilitates aldol reactions, Michael additions, and metal-catalyzed C–C bond formations. The molecule exhibits good bench stability and compatibility with common protecting group strategies, making it well-suited for iterative synthesis in medicinal chemistry and natural product derivatization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: