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CS-W001157 4
Total: USD 88.00

6-Chloro-9-ethyl-9h-purine

  • CAS No. 5462-86-2

  • Cat. No. CS-0216863
  • Purity≥96%
  • MDL No.None
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Chloro-9-ethyl-9h-purine|CS-0216863

Structure of 5462-86-2

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Description

6-Chloro-9-ethyl-9H-purine is a bench-stable purine derivative featuring a chlorine atom at the 6-position and an ethyl group at the 9-position. This configuration imparts enhanced electronic modulation and improved solubility in organic solvents, facilitating its use in medicinal chemistry applications. The molecule serves as a key scaffold for synthesizing nucleoside analogs and kinase inhibitors.

Application

6-Chloro-9-ethyl-9H-purine serves as a versatile building block in purine-based synthesis, enabling efficient access to nucleoside analogs and heterocyclic scaffolds. Its chlorine at the 6-position provides a reliable site for palladium-catalyzed cross-coupling reactions, while the 9-ethyl group enhances solubility and stability under standard reaction conditions. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for medicinal chemistry campaigns and scale-up applications.

General Information

  • CAS No. 5462-86-2
  • Cat. No. CS-0216863
  • Purity ≥96%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇ClN₄
  • Molecular Weight 182.61
  • Synonym(s) 6-Chloro-9-ethylpurine
  • SMILES CCN1C=NC2=C(Cl)N=CN=C21

Computational Chemistry Data

  • TPSA   43.6
  • LogP   1.4996
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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