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Structure of 54903-16-1
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2-Oxo-2,3-dihydro-1,3-benzoxazole-6-carboxylic acid features a fused heterocyclic core with a carboxylic acid at the 6-position, enabling direct conjugation in synthetic workflows. The oxazole ring imparts stability and electron-deficient character, facilitating coupling reactions under mild conditions. This scaffold integrates readily into bioactive molecule design, particularly for kinase inhibitors and pharmaceutical intermediates.
2-Oxo-2,3-dihydro-1,3-benzoxazole-6-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard amide coupling and electrophilic substitution reactions. Its carboxylic acid functionality facilitates direct derivatization, while the fused benzoxazole core provides metabolic stability and enhanced binding affinity in target-directed scaffolds. The compound exhibits good bench stability and is readily purified by recrystallization, supporting its use in scalable route development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: