Z-Tyr-OBzl

Name: Z-Tyr-OBzl
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 5513-40-6
Cat. No. CS-0149875
Purity≥95%
MDL No.MFCD00136670

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HazMat Fee

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

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Description

Z-Tyr-OBzl features a protected tyrosine residue with a benzyl ester group and a carbobenzoxy (Z) amine protector, enabling stable incorporation into peptide chains. The para-hydroxyl group remains accessible for selective derivatization. This derivative facilitates efficient synthesis of phosphorylation-mimetic sequences in solid-phase peptide synthesis workflows.

Application

Z-Tyr-OBzl serves as a robust dipeptide building block for peptide synthesis, enabling efficient N-terminal protection and side-chain stabilization. The benzyloxycarbonyl (Z) group provides reliable amine protection, while the benzyl ester (OBzl) offers orthogonal deprotection compatibility. This combination facilitates smooth coupling reactions, enhances solubility in organic solvents, and supports high-yielding transformations under standard conditions—ideal for iterative solid-phase and solution-phase peptide assembly.

General Information

CAS No. 5513-40-6
Cat. No. CS-0149875
Purity ≥95%
MDL No. MFCD00136670
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₄H₂₃NO₅
Molecular Weight 405.44
Synonym(s) Cbz-L-Tyrosine benzyl ester
SMILES O=C([C@@H](NC(OCC1=CC=CC=C1)=O)CC2=CC=C(O)C=C2)OCC3=CC=CC=C3

Computational Chemistry Data

TPSA 84.86
LogP 3.9731
H_Acceptors 5
H_Donors 2
Rotatable_Bonds 8

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Tyrosine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

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Z-Tyr-OBzl

CAS No. 5513-40-6

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