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Structure of 55276-43-2
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1-(Methylsulfonyl)piperazine is a bench-stable, electron-deficient heterocycle featuring a polar methylsulfonyl group that enhances solubility and metabolic stability. This functionalized piperazine integrates readily into medicinal chemistry scaffolds, serving as a key building block for bioactive molecules in drug discovery programs.
1-(Methylsulfonyl)piperazine serves as a versatile, bench-stable building block in medicinal chemistry, enabling the introduction of a polar, metabolically robust sulfonamide moiety. Its amine functionality facilitates straightforward derivatization via nucleophilic substitution or reductive amination, while the methylsulfonyl group enhances solubility and modulates pharmacokinetic properties. This compound functions effectively in the construction of heterocyclic scaffolds and bioactive molecules requiring controlled polarity and hydrogen-bonding capacity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: