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CS-W001157 4
Total: USD 88.00

1-Boc-4-(4-fluorophenyl)-4-hydroxypiperidine

  • CAS No. 553631-05-3

  • Cat. No. CS-0210800
  • Molecule weight295.35
  • Purity≥97%
  • MDL No.MFCD09953399

*For research and further manufacturing use only, not for direct human use.

1-Boc-4-(4-fluorophenyl)-4-hydroxypiperidine|CS-0210800

Structure of 553631-05-3

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General Information

  • CAS No. 553631-05-3
  • Cat. No. CS-0210800
  • Purity ≥97%
  • MDL No. MFCD09953399
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₂FNO₃
  • Molecular Weight 295.35
  • Synonym(s) tert-Butyl 4-(4-fluorophenyl)-4-hydroxypiperidine-1-carboxylate
  • SMILES CC(C)(C)OC(=O)N1CCC(CC1)(C2=CC=C(C=C2)F)O

Synthesis

  • Route1
    • null|null
      79099-07-3
    • null|null
      352-13-6
    • ~76%
    • 1-Boc-4-(4-fluorophenyl)-4-hydroxypiperidine|CS-0210800
      553631-05-3

    References

    • Gruenenthal GmbH Patent: US2009/264400 A1, 2009 ; Location in patent: Page/Page column 65 ; US 20090264400 A1
  • Route2
    • null|null
      79099-07-3
    • null|null
      460-00-4
    • ~74%
    • 1-Boc-4-(4-fluorophenyl)-4-hydroxypiperidine|CS-0210800
      553631-05-3

    References

    • ABBOTT LABORATORIES; ABBOTT LABORATORIES TRADING (SHANGHAI) COMPANY, LTD.; WANG, Xueqing; MEYER, Michael; YAO, Betty; GUO, Tao; WEI, Guo Ping,Robert; WANG, Lijuan, Jane Patent: WO2013/10453 A1, 2013 ; Location in patent: Page/Page column 128-129 ;
  • Route3
    • null|null
      79099-07-3
    • null|null
      225916-39-2
    • ~63%
    • 1-Boc-4-(4-fluorophenyl)-4-hydroxypiperidine|CS-0210800
      553631-05-3

    References

    • Bouffard, Jean; Itami, Kenichiro Organic Letters, 2009 , vol. 11, # 19 p. 4410 - 4413

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   49.77
  • LogP   3.0442
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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