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2-Bromooctane

  • CAS No. 557-35-7

  • Cat. No. CS-0182749
  • Molecule weight193.12
  • Purity≥98%
  • MDL No.MFCD00040823

*For research and further manufacturing use only, not for direct human use.

2-Bromooctane|CS-0182749

Structure of 557-35-7

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General Information

  • CAS No. 557-35-7
  • Cat. No. CS-0182749
  • Purity ≥98%
  • MDL No. MFCD00040823
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₇Br
  • Molecular Weight 193.12
  • Synonym(s) sec-Octyl bromide (VAN)
  • SMILES CC(Br)CCCCCC

Description

2-Bromooctane is a linear alkyl bromide featuring a reactive C–Br bond at the second carbon. This primary halide facilitates nucleophilic substitution reactions under standard conditions, serving as a reliable precursor in synthetic organic chemistry. Its moderate chain length provides favorable solubility and handling characteristics for bench-scale transformations.

Application

2-Bromooctane serves as a versatile alkylating agent in organic synthesis, enabling efficient C–C bond formation via nucleophilic substitution reactions. Its primary alkyl bromide functionality exhibits high reactivity with a range of nucleophiles, including thiols, amines, and carbon-centered anions. The linear octyl chain provides favorable solubility and stability under standard reaction conditions, facilitating straightforward purification and scalability in synthetic workflows. This compound functions reliably in the construction of longer-chain alkyl derivatives and serves as a key intermediate in the preparation of functionalized hydrocarbons for industrial and pharmaceutical applications.

Synthesis

  • Route1
    • null|null
      4128-31-8
    • In-stock
      Ammonium acetate, for molecular biology, 98%|CS-0646220
      631-61-8
    • ~3%
    • null|null
      74112-36-0
    • In-stock
      2-Bromooctane|CS-0182749
      557-35-7

    References

    • Tetrahedron Letters, , vol. 54, # 14 p. 1813 - 1816
  • Route2
    • null|null
      4128-31-8
    • ~99%
    • In-stock
      2-Bromooctane|CS-0182749
      557-35-7

    References

    • Desmaris, Laurence; Percina, Nathalie; Cottier, Louis; Sinou, Denis Tetrahedron Letters, 2003 , vol. 44, # 41 p. 7589 - 7591
  • Route3
    • null|null
      1028-12-2
    • ~95%
    • In-stock
      2-Bromooctane|CS-0182749
      557-35-7

    References

    • Haire, D. L.; anzen, Edward G. Canadian Journal of Chemistry, 1982 , vol. 60, p. 1514 - 1522

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319
Precautionary Statements : P210-P264-P280-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.7402
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   5

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