Lot numbers can be found on the outside label of a product:
L-Glutamic acid
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CAS No. 56-86-0
- Cat. No. CS-0003473
- Purity≥98%
- MDL No.MFCD00002634
*For research and further manufacturing use only, not for direct human use.
Structure of 56-86-0
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General Information
- CAS No. 56-86-0
- Cat. No. CS-0003473
- Purity ≥98%
- MDL No. MFCD00002634
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₅H₉NO₄
- Molecular Weight 147.13
- Synonym(s) (2S)-2-Aminopentanedioic acid;H-Glu-OH;L(+)-Glutamic acid
- SMILES OC(CC[C@H](N)C(O)=O)=O
Description
Methyl 2-oxobutanoate can be used as a starting material:To synthesize indole derivatives via Fischer indolization of arylhydrazines using propylphosphonic anhydride.In the synthesis of ()-picrotoxinin, a natural product and neurotoxic sesquiterpenoid.To prepare the core structure of phalarine, a natural product found in perennial grass.
Application
L-Glutamic acid serves as a key building block in peptide synthesis and metabolic pathway studies, offering well-established reactivity at both α- and γ-carboxylate sites. Its amphoteric nature and stability under standard bench conditions facilitate straightforward functionalization, protection, and coupling protocols. Widely utilized in the synthesis of bioactive peptides and heterocyclic scaffolds, it functions as a reliable precursor for neurotransmitter analogs and enzyme substrate models.
Synthesis
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Route1
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91871-28-2 - ~99%
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In-stock
56-86-0
References
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Luo, Jin; Smith, Michael D.; Lantrip, Douglas A.; Wang, Susan; Fuchs Journal of the American Chemical Society, 1997 , vol. 119, # 42 p. 10004 - 10013
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Route2
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570429-70-8
- ~77%
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In-stock
56-86-0
References
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Oba, Makoto; Nishiyama, Naohiro; Nishiyama, Kozaburo Tetrahedron, 2005 , vol. 61, # 35 p. 8456 - 8464
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References
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Journal of the American Chemical Society, , vol. 102, # 15 p. 5115 - 5117
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 100.62
- LogP -0.7369
- H_Acceptors 3
- H_Donors 3
- Rotatable_Bonds 4
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Key Words
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