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CS-W001157 4
Total: USD 88.00

6-Bromo-8-fluoro-2H-benzo[b][1,4]oxazin-3(4H)-one

  • CAS No. 560082-53-3

  • Cat. No. CS-0142287
  • Molecule weight246.03
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-Bromo-8-fluoro-2H-benzo[b][1,4]oxazin-3(4H)-one|CS-0142287

Structure of 560082-53-3

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General Information

  • CAS No. 560082-53-3
  • Cat. No. CS-0142287
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅BrFNO₂
  • Molecular Weight 246.03
  • Synonym(s) 6-BROMO-8-FLUORO-4H-BENZO[1,4]OXAZIN-3-ONE
  • SMILES O=C1COC2=C(F)C=C(Br)C=C2N1

Synthesis

  • Route1
    • In-stock
      2-Amino-4-bromo-6-fluorophenol|CS-0112406
      182499-89-4
    • null|null
      79-04-9
    • ~63%
    • In-stock
      6-Bromo-8-fluoro-2H-benzo[b][1,4]oxazin-3(4H)-one|CS-0142287
      560082-53-3

    References

    • GLAXO GROUP LIMITED Patent: WO2006/14580 A1, 2006 ; Location in patent: Page/Page column 52 ;
  • Route2
    • null|null
      943994-29-4
    • ~81%
    • In-stock
      6-Bromo-8-fluoro-2H-benzo[b][1,4]oxazin-3(4H)-one|CS-0142287
      560082-53-3

    References

    • Hameed P., Shahul; Shanbhag, Gajanan; Shinde, Vikas; Chinnapattu, Murugan; Manjrekar, Praveena; Puttur, Jayashree; Patil, Vikas; Ugarkar, Bheemarao Synthetic Communications, 2013 , vol. 43, # 24 p. 3315 - 3321
  • Route3

    References

    • Journal of Medicinal Chemistry, , vol. 54, # 24 p. 8616 - 8631

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P264-P270-P330

Quality Control

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   1.9191
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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