H-DL-Ser-OMe.HCl

Name: H-DL-Ser-OMe.HCl
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 5619-04-5
Cat. No. CS-W014338
Purity≥98%
MDL No.MFCD00012593

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 5619-04-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 5619-04-5
Cat. No. CS-W014338
Purity ≥98%
MDL No. MFCD00012593
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₁₀ClNO₃
Molecular Weight 155.58
Synonym(s) None
SMILES COC(C(N)CO)=O.Cl

Description

H-DL-Ser-OMe.HCl features a methyl ester-protected serine residue with balanced solubility and stability under standard conditions. This derivative serves as a key chiral building block in peptide synthesis, enabling efficient coupling without racemization. The hydrochloride salt enhances handling and storage reliability.

Application

H-DL-Ser-OMe·HCl serves as a stable, bench-ready chiral building block for peptide synthesis and medicinal chemistry. The N-terminal amine is protected as a hydrochloride salt, enabling straightforward handling and solubility in polar solvents. The O-methyl ester group provides enhanced stability against hydrolysis while remaining compatible with standard coupling protocols. This derivative facilitates efficient incorporation into peptidomimetics and heterocyclic scaffolds through well-established amide bond formation and side-chain functionalization reactions.

Synthesis

Route1
- 67-56-1
- 119254-72-7
- ~95%
- In-stock
  
  5619-04-5
References
- Effenberger, Franz; Zoller, Gerhard Tetrahedron, 1988 , vol. 44, # 17 p. 5573 - 5582
Route2
- 67-56-1
- In-stock
  
  302-84-1
- ~95%
- In-stock
  
  5619-04-5
References
- Thacker, Nathan C.; Molnar-Toth, Judit; Miska, Judy L.; Barletta, Raul G.; Takacs, James M. Heterocycles, 2012 , vol. 86, # 2 p. 1575 - 1582

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 72.55
LogP -1.0992
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 2

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Serine and derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids C-ProtectedAmino Acids

Key Words

H-DL-Ser-OMe.HCl sigmaH-DL-Ser-OMe.HCl manufacturerH-DL-Ser-OMe.HCl priceH-DL-Ser-OMe.HCl structureH-DL-Ser-OMe.HCl SDSbuy H-DL-Ser-OMe.HClH-DL-Ser-OMe.HCl supplierH-DL-Ser-OMe.HCl usesH-DL-Ser-OMe.HCl molecular weightprice of H-DL-Ser-OMe.HClH-DL-Ser-OMe.HCl chemical name formula of H-DL-Ser-OMe.HCl

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

H-DL-Ser-OMe.HCl

CAS No. 5619-04-5

Recommended Products