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CS-W001157 4
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2-(Benzo[d]thiazol-2-yl)acetonitrile

  • CAS No. 56278-50-3

  • Cat. No. CS-M0204
  • Purity≥98%
  • MDL No.MFCD00051633
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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

2-(Benzo[d]thiazol-2-yl)acetonitrile|CS-M0204

Structure of 56278-50-3

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Description

2-(Benzo[d]thiazol-2-yl)acetonitrile integrates a benzo[d]thiazole scaffold with a nitrile-functionalized acetyl side chain, delivering a robust heterocyclic building block. This structure combines electron-deficient aromatic character with a reactive nitrile group, enabling direct coupling in cross-coupling and condensation reactions. The molecule exhibits enhanced solubility and stability under standard conditions, facilitating use in synthetic workflows requiring precise functionalization.

Application

2-(Benzo[d]thiazol-2-yl)acetonitrile serves as a versatile building block in heterocyclic synthesis, enabling efficient access to benzo[d]thiazole-based scaffolds. Its nitrile group facilitates nucleophilic addition and cyclization reactions, while the fused aromatic system ensures stability and compatibility with standard synthetic protocols. Functions effectively in transition-metal-catalyzed couplings and offers predictable reactivity for medicinal chemistry and materials applications.

General Information

  • CAS No. 56278-50-3
  • Cat. No. CS-M0204
  • Purity ≥98%
  • MDL No. MFCD00051633
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆N₂S
  • Molecular Weight 174.22
  • Synonym(s) Benzothiazole-2-acetonitrile
  • SMILES N#CCC1=NC2=CC=CC=C2S1

Computational Chemistry Data

  • TPSA   36.68
  • LogP   2.36238
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H312+H332-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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