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Structure of 56341-41-4
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5-Fluoro-2-oxoindoline delivers a sterically accessible, electron-deficient scaffold ideal for transition-metal-catalyzed coupling and cyclization reactions. This bench-stable heterocycle integrates readily into complex molecular architectures, offering enhanced reactivity at the C5 position due to the fluorine substituent’s inductive effect.
5-Fluoro-2-oxoindoline serves as a versatile building block in medicinal chemistry, enabling efficient construction of indole-based scaffolds. Its electron-deficient aromatic ring and amide functionality facilitate electrophilic substitution, Pd-catalyzed coupling, and cyclization reactions. Bench-stable and readily purified by chromatography, it functions effectively in multi-step syntheses of kinase inhibitors and CNS-targeted compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: