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Structure of 56632-83-8
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This fluorinated nucleoside analog integrates a 2’-fluoro substitution on a β-D-arabinofuranose sugar, enhancing metabolic stability and resistance to enzymatic degradation. The arabinose configuration imparts distinct conformational rigidity, improving binding affinity in antiviral and anticancer applications.
2’-Deoxy-2’-fluoro-β-D-arabinocytidine serves as a stable nucleoside analog enabling efficient incorporation into oligonucleotides via standard phosphoramidite chemistry. Its 2′-fluoro substitution enhances nuclease resistance while maintaining favorable sugar pucker conformation, facilitating robust hybridization and improved pharmacokinetic properties in antisense applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: