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Structure of 567-19-1
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3-Chlorobenzo[d]isothiazole 1,1-dioxide features a fused heterocyclic core with a sulfone group enhancing electronic polarization and stability. This electron-deficient scaffold integrates readily into synthetic sequences requiring strong acceptor character. The chlorine substituent provides a handle for downstream functionalization via nucleophilic substitution or cross-coupling reactions. Bench-stable and moisture-tolerant, it serves as a robust building block in medicinal chemistry and materials synthesis.
3-Chlorobenzo[d]isothiazole 1,1-dioxide serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of bioactive scaffolds through well-established coupling reactions. Its electron-deficient isothiazole core facilitates nucleophilic substitution and transition-metal-catalyzed transformations, while the sulfonamide-like dioxide group enhances solubility and metabolic stability. Bench-stable and compatible with diverse functional groups, it functions reliably in multi-step synthesis and process development workflows.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: