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(2,3-Dimethylphenyl)hydrazine hydrochloride

  • CAS No. 56737-75-8

  • Cat. No. CS-0153610
  • Purity≥95%
  • MDL No.MFCD00013380

*For research and further manufacturing use only, not for direct human use.

(2,3-Dimethylphenyl)hydrazine hydrochloride|CS-0153610

Structure of 56737-75-8

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General Information

  • CAS No. 56737-75-8
  • Cat. No. CS-0153610
  • Purity ≥95%
  • MDL No. MFCD00013380
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₃ClN₂
  • Molecular Weight 172.66
  • Synonym(s) 2,3-DIMETHYLPHENYLHYDRAZINE HCL
  • SMILES CC1=C(C)C(=CC=C1)NN.Cl

Description

This bench-stable hydrazine derivative features a sterically hindered aryl group that enhances reactivity control in coupling processes. The para-methyl substitution pattern increases electron density at the hydrazine nitrogen, facilitating selective imine formation and enabling efficient integration into complex heterocyclic scaffolds under mild conditions.

Application

(2,3-Dimethylphenyl)hydrazine hydrochloride serves as a reliable building block for heterocyclic synthesis, particularly in the construction of pyrazoles and other nitrogen-containing scaffolds. Its stability under standard bench conditions and compatibility with diverse coupling reactions enable efficient access to biologically relevant frameworks. The hydrazine functionality facilitates condensation with carbonyl compounds, offering a practical route to substituted heterocycles used in medicinal chemistry and agrochemical research.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   2.01084
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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