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Structure of 569370-39-4
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3-Formyl-5-(trifluoromethyl)benzonitrile features a trifluoromethyl group and a nitrile moiety flanking an aldehyde function, creating a highly electron-deficient aromatic core. This arrangement enables direct integration into heterocyclic synthesis, particularly in the development of bioactive scaffolds requiring strong dipole interactions and enhanced metabolic stability. The molecule exhibits excellent solubility in common organic solvents and maintains stability under standard bench conditions.
3-Formyl-5-(trifluoromethyl)benzonitrile serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to complex heterocyclic scaffolds. The ortho-formyl and trifluoromethyl groups provide enhanced reactivity and metabolic stability, while the nitrile moiety facilitates downstream transformations such as amidation, reduction, or cyclization. Bench-stable and compatible with standard synthetic protocols, it functions effectively in multi-step sequences requiring functional group tolerance and predictable regiochemistry.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: