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Structure of 56961-31-0
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2-Chloro-6-hydroxybenzoic acid features a hydroxyl group positioned ortho to the carboxylic acid, enhancing its reactivity in coupling and derivatization reactions. The electron-withdrawing chlorine substituent at the para position stabilizes adjacent charge distributions, facilitating selective functionalization. This combination enables efficient incorporation into bioconjugation scaffolds and pharmaceutical intermediates under standard conditions.
2-Chloro-6-hydroxybenzoic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct functionalization at the ortho-hydroxy and carboxylic acid positions. Its compatibility with standard coupling reactions, such as amide formation and esterification, facilitates rapid derivatization. The molecule exhibits good bench stability and is readily purified by recrystallization, supporting its use in multi-step syntheses of heterocyclic scaffolds and bioactive compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: