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CS-W001157 4
Total: USD 88.00

4'-Bromo-[1,1'-biphenyl]-4-carboxylic acid

  • CAS No. 5731-11-3

  • Cat. No. CS-0033739
  • Purity≥95%
  • MDL No.MFCD00452920
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4'-Bromo-[1,1'-biphenyl]-4-carboxylic acid|CS-0033739

Structure of 5731-11-3

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Description

4'-Bromo-[1,1'-biphenyl]-4-carboxylic acid features a brominated aryl moiety paired with a carboxylic acid group, enabling direct coupling in Suzuki-Miyaura and other transition-metal-catalyzed reactions. The para-substituted biphenyl scaffold ensures planarity and enhanced stability, while the terminal carboxylic acid facilitates derivatization under standard conditions. This compound serves as a robust building block for functionalized biaryls in materials science and medicinal chemistry applications.

Application

4'-Bromo-[1,1'-biphenyl]-4-carboxylic acid serves as a versatile building block for constructing biaryl scaffolds in medicinal chemistry and materials science. Its bromo and carboxylic acid functionalities enable sequential cross-coupling reactions and derivatization under standard conditions. The compound exhibits good bench stability and facilitates efficient purification via recrystallization, making it well-suited for scalable synthesis and library generation.

General Information

  • CAS No. 5731-11-3
  • Cat. No. CS-0033739
  • Purity ≥95%
  • MDL No. MFCD00452920
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₉BrO₂
  • Molecular Weight 277.11
  • Synonym(s) Bromo biphenyl carboxylic acid
  • SMILES O=C(C1=CC=C(C2=CC=C(Br)C=C2)C=C1)O

Computational Chemistry Data

  • TPSA   37.3
  • LogP   3.8143
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P501

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