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Structure of 57351-99-2
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5-Methylisoxazole-3-carbonitrile features a fused heterocyclic core with complementary electron-withdrawing and steric elements. The nitrile group enhances reactivity in cross-coupling, while the methyl substituent improves solubility and metabolic stability. This compound serves as a robust scaffold for medicinal chemistry libraries and functional materials development under standard conditions.
5-Methylisoxazole-3-carbonitrile serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to isoxazole-based scaffolds. Its nitrile group facilitates nucleophilic addition and cyclization reactions, while the methyl substituent enhances metabolic stability and modulates electronic properties. The compound exhibits good bench stability and compatibility with standard coupling protocols, making it well-suited for parallel synthesis and lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3276
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302+H312-H315-H319-H331-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: