Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2,5-Dibromobenzonitrile

  • CAS No. 57381-41-6

  • Cat. No. CS-0131312
  • Purity≥96%
  • MDL No.MFCD00672994

*For research and further manufacturing use only, not for direct human use.

2,5-Dibromobenzonitrile|CS-0131312

Structure of 57381-41-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 57381-41-6
  • Cat. No. CS-0131312
  • Purity ≥96%
  • MDL No. MFCD00672994
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₃Br₂N
  • Molecular Weight 260.91
  • Synonym(s) None
  • SMILES N#CC1=CC(Br)=CC=C1Br

Description

2,5-Dibromobenzonitrile features a sterically hindered aromatic core with two bromine substituents flanking a nitrile group, enabling selective cross-coupling reactions under palladium catalysis. The electron-deficient ring enhances reactivity in nucleophilic substitution processes, while the nitrile moiety serves as a versatile handle for downstream functionalization. This compound exhibits excellent bench stability and moisture tolerance, simplifying handling in synthetic workflows.

Application

2,5-Dibromobenzonitrile serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions such as Suzuki, Stille, and Negishi couplings. The nitrile group provides a handle for downstream functionalization, while the dibromo substitution pattern supports sequential transformations. Its bench stability and compatibility with standard reaction conditions make it a practical choice for constructing complex aromatic scaffolds in medicinal chemistry and materials science.

Synthesis

  • Route1
    • null|null
      100-47-0
    • ~79%
    • In-stock
      2,5-Dibromobenzonitrile|CS-0131312
      57381-41-6

    References

    • Rozen, Shlomo; Brand, Michael; Lidor, Rami Journal of Organic Chemistry, 1988 , vol. 53, # 23 p. 5545 - 5547
  • Route2

    References

    • Du, Bingnan; Jiang, Xiaoqing; Sun, Peipei Journal of Organic Chemistry, 2013 , vol. 78, # 6 p. 2786 - 2791
  • Route3
    • null|null
      3638-73-1
    • ~%
    • In-stock
      2,5-Dibromobenzonitrile|CS-0131312
      57381-41-6

    References

    • Claus; Weil Justus Liebigs Annalen der Chemie, 1892 , vol. 269, p. 219

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   23.79
  • LogP   3.08328
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2,5-Dibromobenzonitrile sigma2,5-Dibromobenzonitrile manufacturer2,5-Dibromobenzonitrile price2,5-Dibromobenzonitrile structure2,5-Dibromobenzonitrile SDSbuy 2,5-Dibromobenzonitrile2,5-Dibromobenzonitrile supplier2,5-Dibromobenzonitrile uses2,5-Dibromobenzonitrile molecular weightprice of 2,5-Dibromobenzonitrile2,5-Dibromobenzonitrile chemical name formula of 2,5-Dibromobenzonitrile
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label