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Structure of 57381-41-6
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2,5-Dibromobenzonitrile features a sterically hindered aromatic core with two bromine substituents flanking a nitrile group, enabling selective cross-coupling reactions under palladium catalysis. The electron-deficient ring enhances reactivity in nucleophilic substitution processes, while the nitrile moiety serves as a versatile handle for downstream functionalization. This compound exhibits excellent bench stability and moisture tolerance, simplifying handling in synthetic workflows.
2,5-Dibromobenzonitrile serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions such as Suzuki, Stille, and Negishi couplings. The nitrile group provides a handle for downstream functionalization, while the dibromo substitution pattern supports sequential transformations. Its bench stability and compatibility with standard reaction conditions make it a practical choice for constructing complex aromatic scaffolds in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: