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CS-W001157 4
Total: USD 88.00

2-Bromo-m-xylene

  • CAS No. 576-22-7

  • Cat. No. CS-W009028
  • Molecule weight185.06
  • Purity≥98%
  • MDL No.MFCD00000075

*For research and further manufacturing use only, not for direct human use.

2-Bromo-m-xylene|CS-W009028

Structure of 576-22-7

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General Information

  • CAS No. 576-22-7
  • Cat. No. CS-W009028
  • Purity ≥98%
  • MDL No. MFCD00000075
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉Br
  • Molecular Weight 185.06
  • Synonym(s) 2,6-Dimethylbromobenzene
  • SMILES CC1=CC=CC(C)=C1Br

Description

2-Bromo-1,3-dimethylbenzene has been used to prepare 2,2,4,6,6-pentamethylbiphenyl.

Application

2-Bromo-m-xylene serves as a versatile aryl halide building block in cross-coupling reactions, enabling efficient construction of substituted biaryls and heterocycles. Its meta-dimethyl substitution pattern provides predictable regiochemistry and enhanced bench stability, facilitating straightforward purification and handling. Functions reliably in Pd-catalyzed coupling protocols, offering consistent yields and broad functional group tolerance in synthetic workflows.

Synthesis

  • Route1
    • null|null
      87-62-7
    • ~49%
    • In-stock
      2-Bromo-m-xylene|CS-W009028
      576-22-7

    References

    • Monatshefte fur Chemie, , vol. 127, # 2 p. 185 - 200
  • Route2
    • null|null
      75-25-2
    • null|null
      103724-97-6
    • ~87%
    • In-stock
      2-Bromo-m-xylene|CS-W009028
      576-22-7

    References

    • Synthesis, , # 6/7 p. 647 - 649
  • Route3

    References

    • US4340757 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319-H335
Precautionary Statements : P210-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P403-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.06594
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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