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Structure of 5765-44-6
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5-Methylisoxazole is a bench-stable heterocycle featuring a methyl-substituted isoxazole core, offering enhanced lipophilicity and metabolic stability. This electron-rich scaffold integrates readily into medicinal chemistry libraries, serving as a robust bioisostere for phenyl and pyridine rings in target-focused lead optimization.
5-Methylisoxazole serves as a versatile heterocyclic building block in medicinal chemistry and synthetic organic research. Its electron-rich ring system enables reliable functionalization at the 3- and 4-positions via electrophilic substitution or transition-metal-catalyzed coupling. The methyl group enhances solubility and metabolic stability, while the isoxazole core provides robustness under standard reaction conditions. This compound functions effectively as a scaffold for API development and exhibits favorable bench stability, ease of purification, and compatibility with diverse functional groups.
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GHS Pictogram :
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GHS No : GHS02
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H225
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501
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Lot numbers can be found on the outside label of a product: