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CS-W001157 4
Total: USD 88.00

2-Methylacetophenone

  • CAS No. 577-16-2

  • Cat. No. CS-W013374
  • Purity≥98%
  • MDL No.MFCD00008734
  • AREC Toxic Substance

*For research and further manufacturing use only, not for direct human use.

2-Methylacetophenone|CS-W013374

Structure of 577-16-2

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General Information

  • CAS No. 577-16-2
  • Cat. No. CS-W013374
  • Purity ≥98%
  • MDL No. MFCD00008734
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O
  • Molecular Weight 134.18
  • Synonym(s) O-Methylacetophenone
  • SMILES CC(C1=CC=CC=C1C)=O

Description

Retinyl palmitate is a vitamin A analog that inhibits cell proliferation and induces cell differentiation. It is used as a dietary supplement as a lipophilic base for eg: soft gelatin capsule. Other applications include as pharmaceutical product which is used for manufacturing aqueous solutions using solubilizing agents such as cremophor. It is also used in the fortification of fatty foods such as margarine, spreads, oils, milk and dairy products. It is used in cosmetics for the preparation of creams and lotions.

Application

2-Methylacetophenone serves as a valuable building block in synthetic organic chemistry, enabling efficient access to substituted aromatic systems and heterocyclic scaffolds. Its ortho-methylated acetophenone structure provides enhanced reactivity in electrophilic substitution and facilitates regioselective functionalization. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for use in medicinal chemistry campaigns and process development workflows.

Synthesis

  • Route1

    References

    • Wang, Qingfu; Du, Wangming; Liu, Tingting; Chai, Huining; Yu, Zhengkun Tetrahedron Letters, 2014 , vol. 55, # 9 p. 1585 - 1588
  • Route2

    References

    • Cornell, Candace N.; Sigman, Matthew S. Journal of the American Chemical Society, 2005 , vol. 127, # 9 p. 2796 - 2797
  • Route3

    References

    • Demizu, Yosuke; Shiigi, Hirofumi; Mori, Hiroyuki; Matsumoto, Kazuya; Onomura, Osamu Tetrahedron Asymmetry, 2008 , vol. 19, # 23 p. 2659 - 2665

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.19762
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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