tert-Butyl 3-hydroxybenzoate

Name: tert-Butyl 3-hydroxybenzoate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 57704-54-8
Cat. No. CS-0143372
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 57704-54-8

Size

Price

Quantity

* Please select Quantity before adding items.

Description

tert-Butyl 3-hydroxybenzoate features a sterically hindered tert-butyl ester group that enhances stability and facilitates selective deprotection under mild acidic conditions. The meta-hydroxyl substituent imparts polarity and enables downstream functionalization, making this compound valuable in synthetic routes requiring controlled reactivity and solubility.

Application

tert-Butyl 3-hydroxybenzoate serves as a versatile synthetic intermediate for the construction of bioactive heterocycles and functionalized aromatic systems. The ortho-hydroxyl group enables direct derivatization via esterification, etherification, or oxidative coupling, while the tert-butyl ester offers robust protection under acidic conditions and facile removal with mild acid. Its bench-stable nature and compatibility with standard coupling reactions make it ideal for medicinal chemistry campaigns requiring selective functionalization of substituted benzoic acid scaffolds.

General Information

CAS No. 57704-54-8
Cat. No. CS-0143372
Purity ≥97%
MDL No. None
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₁₄O₃
Molecular Weight 194.23
Synonym(s) 3-hydroxybenzoic acid tert-butyl ester
SMILES O=C(OC(C)(C)C)C1=CC=CC(O)=C1

Computational Chemistry Data

TPSA 46.53
LogP 2.3475
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Phenol

Building Blocks Functional Group Ester

Key Words

tert-Butyl 3-hydroxybenzoate sigmatert-Butyl 3-hydroxybenzoate manufacturertert-Butyl 3-hydroxybenzoate pricetert-Butyl 3-hydroxybenzoate structuretert-Butyl 3-hydroxybenzoate SDSbuy tert-Butyl 3-hydroxybenzoatetert-Butyl 3-hydroxybenzoate suppliertert-Butyl 3-hydroxybenzoate usestert-Butyl 3-hydroxybenzoate molecular weightprice of tert-Butyl 3-hydroxybenzoatetert-Butyl 3-hydroxybenzoate chemical name formula of tert-Butyl 3-hydroxybenzoate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

tert-Butyl 3-hydroxybenzoate

CAS No. 57704-54-8

Recommended Products