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Structure of 581-45-3
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4-(Piperidin-4-yl)pyridine features a pyridine ring fused to a piperidine moiety, creating a rigid, nitrogen-rich scaffold with enhanced basicity and solubility. This structural motif enables effective coordination in catalytic systems and serves as a key building block in medicinal chemistry, particularly for kinase inhibitors and metal-ligand complexes.
4-(Piperidin-4-yl)pyridine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization protocols. Its pyridine core provides strong hydrogen-bonding capacity and π-stacking potential, while the piperidine moiety offers tunable basicity and conformational flexibility. The compound exhibits excellent bench stability, facilitates straightforward purification, and demonstrates broad compatibility with common reaction conditions, making it well-suited for lead optimization and API synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: