Ethyl 3-(2,4-difluorophenyl)-3-oxopropanoate

Name: Ethyl 3-(2,4-difluorophenyl)-3-oxopropanoate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 58101-23-8
Cat. No. CS-0099788
Purity≥95%
MDL No.MFCD03424828

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Ethyl 3-(2,4-difluorophenyl)-3-oxopropanoate|CS-0099788

Structure of 58101-23-8

Size

Price

Quantity

* Please select Quantity before adding items.

Description

Ethyl 3-(2,4-difluorophenyl)-3-oxopropanoate features a conjugated β-keto ester framework flanked by electron-deficient aryl substituents, enabling efficient enolization and nucleophilic addition. This bench-stable reagent integrates readily into heterocyclic synthesis pathways, particularly in the construction of fluorinated pyran and quinoline derivatives under mild conditions.

Application

Ethyl 3-(2,4-difluorophenyl)-3-oxopropanoate serves as a versatile β-keto ester building block for constructing fluorinated heterocycles and bioactive scaffolds. Its electrophilic α-carbon facilitates nucleophilic addition, condensation, and cyclization reactions under standard conditions. The 2,4-difluorophenyl moiety enhances metabolic stability and modulates electronic properties, making it valuable in medicinal chemistry campaigns. Bench-stable and amenable to straightforward purification, it functions reliably in multistep synthesis workflows.

General Information

CAS No. 58101-23-8
Cat. No. CS-0099788
Purity ≥95%
MDL No. MFCD03424828
Storage RT, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₁₀F₂O₃
Molecular Weight None
Synonym(s) ETHYL-(2,4-DIFLUOROPHENYL)-3-OXOPROPANOATE
SMILES O=C(CC(C1=CC=C(C=C1F)F)=O)OCC

Computational Chemistry Data

TPSA 43.37
LogP 2.1007
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 4

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P233-P260-P261-P264-P271-P280-P302+P352-P304+P340-P340-P362-P403-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Ketone

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

58101-23-8 sigma58101-23-8 manufacturer58101-23-8 price58101-23-8 structure58101-23-8 SDSbuy 58101-23-858101-23-8 supplier58101-23-8 uses58101-23-8 molecular weightprice of 58101-23-858101-23-8 chemical name formula of 58101-23-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Ethyl 3-(2,4-difluorophenyl)-3-oxopropanoate

CAS No. 58101-23-8

Recommended Products