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Structure of 58123-77-6
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3-Hydroxy-4-iodobenzoic acid features a hydroxyl group adjacent to a carboxylic acid, enabling direct functionalization in synthetic sequences. The para-iodo substituent provides a reactive handle for palladium-catalyzed cross-coupling, facilitating the integration of complex aryl motifs into bioactive scaffolds under standard conditions.
3-Hydroxy-4-iodobenzoic acid serves as a versatile building block for the synthesis of functionalized aromatic scaffolds, enabling direct Suzuki-Miyaura and Stille coupling reactions due to its iodine handle. The ortho-hydroxyl and carboxylic acid groups provide complementary reactivity for derivatization, protecting group strategies, and metal coordination. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for medicinal chemistry and process development workflows requiring multi-step transformations.
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GHS Pictogram :
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GHS No : GHS05,GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: