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Structure of 581802-26-8
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This boronate ester features a (E)-configured enol moiety flanked by a methyl group and a tetramethyl-1,3,2-dioxaborolane ring. The conjugated alkene system enables efficient cross-coupling reactions under mild conditions, while the sterically protected boronate offers enhanced stability during storage and handling. This compound integrates readily into complex molecular architectures via Suzuki-Miyaura coupling protocols.
(E)-2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)but-3-en-2-ol serves as a stable, bench-ready boronate building block for palladium-catalyzed cross-coupling reactions. Its vinyl boronate functionality enables efficient Suzuki-Miyaura coupling with aryl, heteroaryl, and vinyl halides under mild conditions. The tetramethylcyclohexadienylboronate moiety enhances stability and minimizes protodeboronation, while the tertiary alcohol group provides orthogonal reactivity in multi-step syntheses. Functions reliably in complex molecule assembly and API intermediate construction.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: