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Structure of 581813-17-4
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3-Bromo-4-(trifluoromethyl)benzoic acid features a bromine atom at the meta position and a strongly electron-withdrawing trifluoromethyl group at the para position relative to the carboxylic acid. This combination enhances electrophilic reactivity while maintaining stability under standard conditions, enabling direct functionalization in cross-coupling reactions. The molecule serves as a key scaffold for synthesizing bioactive compounds and advanced materials.
3-Bromo-4-(trifluoromethyl)benzoic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its bromo group enables palladium-catalyzed cross-coupling reactions, while the trifluoromethyl and carboxylic acid functionalities offer enhanced metabolic stability and strategic points for derivatization. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic campaigns in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: