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Structure of 58310-28-4
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(Difluoromethyl)triphenylphosphonium bromide delivers a unique trifluoromethyl analog for nucleophilic fluorination reactions. This bench-stable reagent features a highly electrophilic difluoromethyl group flanked by three aromatic rings, enabling efficient C–F bond formation under mild conditions. The phosphonium center facilitates smooth reaction progression without requiring specialized handling.
(Difluoromethyl)triphenylphosphonium bromide serves as a reliable source of the difluoromethyl group in nucleophilic trifluoromethylation reactions. It functions as a stable, bench-ready reagent for constructing C–CF₂H bonds in heterocyclic and aromatic systems, enabling efficient access to fluorinated scaffolds relevant to medicinal chemistry. The phosphonium salt exhibits good functional group tolerance and facilitates straightforward purification, making it well-suited for routine synthetic applications in drug discovery and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: